Prebiotics are food ingredients that induce the growth or activity of beneficial microorganisms. The most common example is in the gastrointestinal tract, where prebiotics can alter the composition of organisms in the gut microbiome.
Experiencing side effects of prebiotic supplementation is very unusual. However, in high doses, supplementing with prebiotics can cause mild abdominal pain, gas, and bloating. By far, the benefits of prebiotics outweigh any of the mild and rare side effects.
Indications and challenges of probiotics, prebiotics, and synbiotics in the management of arthralgias and spondyloarthropathies in inflammatory bowel disease.